UFC 281 — Israel Adesanya vs. Alex Pereira: Fight card, odds, start time, date, location, complete guide

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It’s time for UFC 281. The MMA juggernaut returns to Madison Square Garden in New York with a loaded card sure to entice fans. The marquee is headlined by a pair of title fights. Middleweight champion Israel Adesanya will look to conintue his remarkable run in the division when he welcomes an old foe to the fray in Alex Pereira. The Brazilian slugger owns a pair of victories over Adesanya in kickboxing and has quickly made the transition into this title opportunity in just his sixth MMA fight.

The other title on the line will be the women’s strawweight crown when Carla Esparza looks to make her first defense of the 115-pound strap against former titleholder Weili Zhang. Esparza is in her second reign with the title after winning the inaugural title in 2014 over Rose Namajunas. Zhang bounced back from her title loss to Namajunas with a thunderous knockout of Joanna Jedrzejczyk.

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Plus, a lightweight fire fight is set for the featured bout when former title challengers Dustin Poirier and Michael Chandler link up. The fight could catapult the winner into one final title shot in 2023. The card also sees the final fight of Frankie Edgar’s storied career when he takes on Chris Gutierrez at bantamweight. And lightweights open the show on the main card when Dan Hooker takes on Claudio Puelles.

Below is the complete fight card with the latest odds from Caesars Sportsbook. Be sure to check back in on this page to get our live coverage with play-by-play and round-by-scoring of each main card bout.

Follow along with compete coverage of UFC 281 live from Madison Square Garden for round-by-round scoring and play-by-play of all the action inside the Octagon beginning at 7:30 p.m. ET.

UFC 281 fight card, odds

  • Israel Adesanya (c) -220 vs. Alex Pereira +180, middleweight championship
  • Weili Zhang -340 vs. Carla Esparza (c) +270, women’s strawweight championship
  • Dustin Poirier def. Michael Chandler via third-round submission (rear-naked choke)
  • Chris Gutierrez def. Frankie Edgar via first-round knockout (knee)
  • Dan Hooker def. Claudio Puelles via second-round knockout (body kick)
  • Renato Moicano def. Brad Riddell via first-round submission (rear naked choke)
  • Ryan Spann def. Dominick Reyes via first-round knockout (punch)
  • Erin Blanchfield  def. Molly McCann via first-round submission (kimura)
  • Andre Petroski def. Wellington Turman via unanimous decision (30-27, 30-27, 29-28)
  • Matt Frevola def. Ottman Azaitar via first-round knockout (punch)
  • Karolina Kowalkiewicz def. Silvana Gomez Juarez via unanimous decision (29-28, 29-28, 29-28)
  • Michael Trizano def. Choi Seung-woo via first-round TKO (punches)
  • Montel Jackson def. Julio Arce via unanimous decision (30-27, 30-27, 29-28)
  • Carlos Ulberg def. Nicolae Negumereanu via first-round TKO (punches)

UFC 281 info

  • Date: Nov. 12
  • Location: Madison Square Garden — New York City
  • Start time: 10 p.m. ET (Main card) 
  • How to watch: ESPN+ PPV | Price: $74.99

UFC 281 countdown

Who wins Adesanya vs. Pereira? And how exactly does each fight end? Visit SportsLine now to get detailed picks on every fight at UFC 281, all from the incomparable expert who’s up more than $13,000 on MMA in the past three years, and find out.